Toxicity of cellulose fibres
Respirable cellulose fibres were less toxic in vitro than the mineral fibres crocidolite and MMVF10. Short-term inhalation of cellulose caused an inflammatory lung response which resolved despite continuing exposure. Intraperitoneal injection of cellulose fibres induced sarcomas rather than mesotheliomas at the highest dose (10 9 WHO fibres), while the two middle doses (10 7 and 10 8 fibres) each produced a mesothelioma. Further work is required to examine the pulmonary effects of respirable cellulose fibres.
Publication Number: P/02/09
First Author: Cullen RT
Other Authors: Miller BG , Jones AD , Davis JMG
Publisher: ,,
Download PublicationCOPYRIGHT ISSUES
Anyone wishing to make any commercial use of the downloadable articles on this page should contact the publishers of the journals. Please see the copyright notices on the journals' home pages:
- Annals of Occupational Hygiene
- Occupational and Environmental Medicine
- American Journal of Respiratory Cell and Molecular Biology
- QJM: An International Journal of Medicine
- Occupational Medicine
Permissions requests for Oxford Journals Online should be made to: [email protected]
Permissions requests for Occupational Health Review articles should be made to the editor at [email protected]